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We welcome inquiries from highly qualified scientists at all levels from graduate students to senior staff scientists interested in joining our research team and collaborative network to study the genomics of human disease.

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Current Opportunities:

We are seeking exceptional postdoctoral candidates in computational biology, bioinformatics, and/or statistical genetics. Candidates would direct collaborative research initiatives seeking to discover genomic variation and determine its functional impact in developmental anomalies and neuropsychiatric disorders. Highly qualified candidates would oversee one or more of the following studies: (1) analyses related to the aggregation of datasets across global populations to discover structural variation, principles of natural selection, and insights into population genetics (e.g. the genome aggregation database [gnomAD]); (2) large-scale Mendelian and complex disease association studies; (3) functional genomics analyses from human iPSC-derived neuronal cells or three-dimensional organoid models modified using CRISPR/Cas9 genome editing.

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We are seeking exceptional postdoctoral candidates in computational biology, bioinformatics, and/or statistical genetics. We are seeking a candidate to perform genomics research across a spectrum of population genetics, disease association, and functional genomics studies. Successful candidates are expected to excel at critical thinking, be quick learners for new analytical approaches, and capable of applying or developing novel computational methods for solving complex problems. Candidates must have a doctoral degree (PhD or MD), an excellent publication record, and great communication skills. A strong background in computer science and/or mathematics is required; and specifically, experience with analyzing high-dimensional datasets is preferred. Some fluency with biology and/or neuroscience is ideal, as is the ability to adapt quickly to a cross-functional team in a rapidly changing environment.

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We are seeking a motivated, enthusiastic, experienced staff scientist to lead the CGM Genomics and Technology Core (GTC). The GTC is the primary genomics hub for the CGM, which encompasses 46 faculty engaged in all facets of human genetics and genomics research. The GTC is committed to the development and application of innovations in genomics methods for exome, genome, transcriptome, epigenome, and multiple other ‘omics technologies. The GTC provides all genomics research solutions, including molecular genomics and bioinformatics support, for CGM faculty and research programs within and outside the MGH, Harvard Medical School, and Broad Institute Communities. The candidate will lead the GTC and oversee the genomics programs within the Talkowski laboratory, which will include personnel management and training, project and program management, budget management, development and maintenance of standardized protocols and processes, as well as widespread interactions with faculty across our communities and institutions. Exceptional candidates will have extensive experience in genomics technology development and library production, in addition to outstanding organizational, interpersonal, and leadership skills.

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We are seeking a research technician or technologist with a Bachelor’s degree in biology, biochemistry, or a related discipline. The candidate should have at least 1 year of experience in DNA/RNA extraction, PCR/qPCR, gel electrophoresis, mammalian cell culture, and genomic sequencing.

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