Genome Aggregation Database (gnomAD)
The Genome Aggregation Database (gnomAD) is a coalition of investigators seeking to aggregate and harmonize exome and genome sequencing data from a variety of large-scale sequencing projects, and to make summary data available for the wider scientific community. The project is overseen by co-directors Heidi Rehm and Mark Daly, and council members Daniel MacArthur, Benjamin Neale, Michael Talkowski, Anne O’Donnell-Luria, Grace Tiao, Matthew Solomonson, and Kat Tarasova. The second release spans 125,748 exome sequences and 15,708 whole-genome sequences from unrelated individuals sequenced as part of various disease-specific and population genetic studies. The v3.1.2 data set (GRCh38) spans 76,156 genomes of diverse ancestries, selected as in v2.