Chelsea joined the Talkowski laboratory in September 2017 as a postdoctoral fellow, after completing her PhD in Medical Science with Anne Bassett at the University of Toronto in Canada. In the Talkowski laboratory Chelsea will be working on the Developmental Genome Anatomy Project (DGAP) using whole-genome sequencing and computational tools to help identify new genetic [...]
Xuefang joined the Talkowski lab in June 2017 as a postdoc fellow after receiving a Ph.D in Bioinformatics and a Masters in Statistics from the University of Michigan at Ann Arbor. She will be working as a member of the structural variation team pursuing applications of structural variation methods development to human disease cohort, with [...]
The Talkowski Lab is thrilled to announce the awarding of a fellowship grant to two of our PhD students, Ryan Collins and Kiana Mohajeri. Both Kiana and Ryan were awarded the Graduate Research Fellowship from the NSF in the field of genomics. Ryan and Kiana were chosen out of over 13,000 applications. There were a [...]
Derek Tai, a Postdoctoral Fellow in the Talkowski Lab since 2013 comments on the lab's most recent Nature Neuroscience paper of which he is first author: "Recently, we developed a new CRISPR approach which can directly target perfectly homologous sequences in the segmental duplications and model the reciprocal dosage imbalances that occur via NAHR mechanisms. [...]
Ryan has accepted an offer to join the Bioinformatics and Integrative Genomics (BIG) PhD program at Harvard Medical School. He will be starting his PhD at HMS in fall 2016 and intends to continue his research on structural variation and genome architecture in human diseases into this next career stage as a PhD student.
Joseph Glessner has been awarded the Executive Committee On Research (ECOR) Tosteson & Fund for Medical Discovery (FMD) Postdoctoral Fellowship Award (15-2) for 9/1/2015-8/31/2016.
In a recently published manuscript, we demonstrated the potential impact of complex and cryptic chromosomal abnormalities in children with early onset neuropsychiatric disorders. In this study, we find that the mainstay of genetic testing for prenatal and pediatric developmental anomalies of unknown etiology, clinical microarray to detect copy number variants (CNVs), is insufficient to detect [...]
We published the first transcriptome sequencing study of a common, recurrent genomic disorder, 16p11.2 microdeletion and duplication. This reciprocal copy number variant (CNV) syndrome is among the most common known causes of autism, and confers risk to a spectrum of development and psychiatric disorders. Our study in lymphoblastoid cell lines from human families and cortical [...]
