Expectations and blind spots for structural variation detection from long-read assemblies and short-read genome sequencing technologies

By |2023-05-10T15:13:14-04:00October 5th, 2022|Categories: Publication|Tags: , , |

In this study, we conducted in-depth analyses to evaluate the power of different sequencing technologies, including long-read and short-read whole genome sequencing (WGS), in discovering genomic structural variation (SV). Our study revealed that albeit the over two-fold increase in the power of SV discovery by long-read sequences when compared against short reads, vast majority of [...]