Rare Coding Variation Provides Insight into the Genetic Architecture and Phenotypic Context of Autism

By |2022-10-24T17:03:27-04:00September 7th, 2022|Categories: Publication|Tags: , |

Leveraging genetic sequencing data of the protein-coding portion of the human genome from more than 60,000 individuals, we found 72 genes to be associated with autism spectrum disorder (ASD) at a stringent threshold of less than 0.1% false discovery rate (FDR). The bulk of the evidence for these implicated genes were contributed by de [...]